PRESENTATION | ACROMAX | SCIENCE NEWS | SERVICES | R+D | TECH.INFO. | GALERY | ||
Mode of action | ||||||||
|
A characteristic of sperm cell membranes is that as ambient temperature rises, the mobility of the lipids in the bilayer plane increases and fatty acid chains become less saturated and shorter. This lateral diffusion of lipids bestows upon the bilayer the fluidity of a liquid. Membrane proteins also show lateral diffusion, though at a slower rate than that of the lipids. However, at the preservation temperature of 15ºC there is virtually no diffusion. The membrane lipids become solidified at this 'low' temperature and their movement is prevented. The movement of membrane proteins is also prevented and the structure of the cell membrane is maintained.
A further process with negative results on semen viability is caused by dead sperm cells liberating metabolites and enzymes into the medium. These are neutralised by ACROMAX ®. The toxicity of dead sperm cells is related to the oxidation of amino acids. The presence of aromatic amino acids leads to the formation of the enzyme peroxidase which is part of the necessary oxidatory machinary. The factors that influence the preservation capacity of boar sperm culture media have been exhaustively studied. This provides the maximum guarantee of maintenance of cellular structures and final performance at fertilization. ACROMAX ® is a boar sperm preservation medium that meets all the requirements of modernday artificial insemination of pigs, and guarantees the initial quality of sperm for 7 - 8 days under adequate storage conditions. |